.Attributes Medicine, Posted online: 18 September 2024 doi:10.1038/ s41591-024-03300-3Genomic and epidemiologic evaluations revealed that an unfamiliar reassortant popular lineage of the Oropouche infection, which has been flowing in the western side Amazon.com region of South america for concerning a decade, is associated with the current individual episodes in between 2022 and also 2024.